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The European Code Against Cancer, 5th edition (ECAC5) comprises 14 recommendations that offer clear, actionable steps for individuals to contribute to cancer prevention, grounded in the latest scientific evidence. Designed for the general population in the European Union (EU), the recommendations are accessible, feasible, and easy to understand.

ECAC5 also includes 14 complementary policy recommendations on population-level measures that may reinforce individual actions. These recommendations urge policy-makers to implement policies that address social, environmental, economic, and structural barriers to healthier behaviours and uptake of preventive interventions.

To provide further details and support the implementation of the 14 recommendations, Knowledge Translation Outputs – in the form of Fact Sheets and Policy Briefs – have been developed to provide more details and explanations for each recommendation. Fact Sheets cater to both a general audience and health professionals. Policy Briefs provide detailed insights for policy-makers and key decision-makers.

The European Code Against Cancer (ECAC) is an initiative of the European Commission, launched as a first edition in 1987. The International Agency for Research on Cancer (IARC/WHO) was requested by the European Commission to produce the 4th edition of ECAC, which was published in 2014. After the adoption of Europe’s Beating Cancer Plan, IARC was re-commissioned to update ECAC for the 5th edition. The project to develop ECAC5 began in 2022, with a 4-year duration, funded by the European Commission under the EU4Health programme. ECAC5 forms a key part of the development of the World Code Against Cancer Framework, for which a series of Regional Codes Against Cancer are being developed that reflect the epidemiological factors specific to each global region.

The ECAC5 recommendations were developed by more than 60 European experts specializing in cancer prevention, epidemiology, health promotion, behavioural change, and communication. The experts were organized into five Working Groups (WGs). The experts in Lifestyle Determinants (WG1), Environmental and Occupational Determinants (WG2), Infections (WG3), and Medical Interventions (WG4) reviewed the latest scientific literature, including producing targeted systematic reviews and meta-analyses, and assessed the most relevant existing international policies that may support each of the recommendations. The experts were supported by the Iberoamerican Cochrane Centre/Research Institute of the Hospital de Sant Pau (Spain), which contributed to the update of the scientific literature, adhering to the methodology of the World Code Against Cancer Framework.

The Communication and Health Literacy Working Group (WG5) provided expert guidance on optimizing the communication of all recommendations, ensuring their coherence as a comprehensive set. In addition to this advisory role, WG5 conducted a large-scale EU study to evaluate the recommendations for individuals, identifying the most effective communication formats to enhance public recall of cancer risk factors.

A Scientific Committee, comprising representatives of major national cancer institutes and governmental agencies across the EU, assessed and approved the recommendations, ensuring that they reflect the latest evidence and are supported by the necessary authoritative policies relevant to the socioeconomic and health systems context of EU Member States. In addition, an Advocacy Group formed by representatives of influential cancer prevention and control entities in the EU, provided further insights and guidance. The ECAC5 project Secretariat was composed of IARC researchers, with support from World Cancer Research Fund International and the European Commission, alongside the Chairs of the five ECAC5 Working Groups, in the Coordination Group.

Working Group 5 Communication & Health Literacy

Role

Name

Institute
Country
Chair

Theresa Marteau

University of Cambridge

United Kingdom
Member

Alina Bârgăoanu

National University of Political Studies and Public Administration

Romania

Member

Kathelijne Bessems

Maastricht University

Netherlands

Member

Janne Bigaard

Danish Cancer Society

Denmark

Member

Kate Brain

University of Cardiff

United Kingdom
Member

Cristiana Fonseca

Portuguese League Against Cancer

Portugal

Member

Ulrike Helbig

German Cancer Aid

Germany

Member

Paweł Koczkodaj

Maria Skłodowska-Curie National Research Institute of Oncology

Poland

Member

Eleni Mantzari

University of Cambridge

United Kingdom
Member

Dafina Petrova

CIBER of Epidemiology and Public Health & Andalusian School of Public Health

Spain

Member

Violaine Roggeri

European Agency for Safety and Health at Work (EU-OSHA)

Spain

Member

Milka Sokolović

European Public Health Alliance (EPHA)

Belgium

Coordination Group

Secretariat

Role

Name
Institute

Co-Principal Investigator

Joachim Schüz

International Agency for Research on Cancer (IARC/WHO)

Co-Principal Investigator

Carolina Espina

International Agency for Research on Cancer (IARC/WHO)

Project Manager

David Ritchie

International Agency for Research on Cancer (IARC/WHO)

Senior Advisor

André Carvalho

International Agency for Research on Cancer (IARC/WHO)

Support to the Secretariat

Role

Name
Institute
Postdoctoral Scientist

Ariadna Feliu

International Agency for Research on Cancer (IARC/WHO) – until August 2024

Postdoctoral Scientist

Erica D’Souza

International Agency for Research on Cancer (IARC/WHO) – until August 2025

Senior Visiting Scientist

Hajo Zeeb

International Agency for Research on Cancer (IARC/WHO)

Secretary

Catherine Chassin

International Agency for Research on Cancer (IARC/WHO)

Chairs of the ECAC5 Working Groups
Name
Working Group
Elio Riboli
Working Group 1: Lifestyles Determinants
Hans Kromhout

Working Group 2: Environmental and Occupational Determinants

Silvia Franceschi

Working Group 3: Infections
Iris Lansdorp-Vogelaar
Working Group 4: Medical Interventions
Dame Theresa Marteau
Working Group 5: Communication and Health Literacy

Representative of the World Cancer Research Fund International (WCRF)

Role

Name
Institute
Senior Advisor
Giota Mitrou
World Cancer Research Fund International (WCRF)
Alternate
Helen Croker
World Cancer Research Fund International (WCRF)

Advocacy Group

Name

Institute

Country

Michele Cecchini
Organisation for Economic Co-operation and Development (OECD)

France

Ciaran Nicholl & Magdalena Stepien

Joint Research Centre – European Commission (JRC)

Italy
Marilys Corbex

WHO Regional Office for Europe (WHO/Europe)

Denmark
Wendy Yared

Association of European Cancer Leagues (ECL)

Belgium

Scientific Committee

Name

Institute

Country

Tit Albreht

National Institute of Public Health (NIJZ)

Slovenia

Silvio Brusaferro (Until August 2024)

Italian National Institute of Health (ISS)

Italy

Joakim Dillner

Karolinska Institutet (KI)

Sweden

Jérôme Foucaud

French National Cancer Institute (INCa)

France

Marta Mańczuk

Maria Skłodowska-Curie National Research Institute of Oncology

Poland

Jose M. Martin Moreno

University of Valencia

Spain

Rene Medema

Princess Máxima Center for Pediatric Oncology

Netherlands

Deirdre Murray

National Cancer Registry Ireland

Ireland

Péter Nagy

National Institute of Oncology

Hungary

Florian Nicula

Formerly, Prof. Dr I. Chiricuta, Oncology Institute

Romania

Mary Nyangasi

World Health Organization (WHO)

Switzerland

Karen Steindorf

German Cancer Research Center (DKFZ)

Germany

Anne Tjønneland

Danish Cancer Society Research Center

Denmark

Working Groups

Working Group 1 Lifestyle Determinants

Role

Name

Institute
Country
Chair
Elio Riboli
Imperial College London
United Kingdom
Deputy Chair
Ioanna Bakogianni
European Commission – Joint Research Centre (JRC)
Italy

Member

Annie Anderson

University of Dundee
United Kingdom

Member

Linda Bauld

University of Edinburgh
United Kingdom

Member

Esteve Fernández

Department of Health, Government of Catalonia

Spain

Member

Michael Leitzmann

University of Regensburg

Germany

Member

Sherry Morris

Imperial College London

United Kingdom

Member

Bernard Srour

INSERM U1153

France

Member

Constantine Vardavas

University of Crete

Greece

Member

Ioana Vlad

World Cancer Research Fund (WCRF) International
United Kingdom

Member

Sabine Vuik

Organisation for Economic Co-operation and Development (OECD)

France

Member

Matty Weijenberg

Maastricht University
Netherlands

Working Group 2 Environmental and Occupational Determinants

Role

Name

Institute
Country
Chair
Hans Kromhout
Utrecht University
Netherlands
Deputy Chair
Nadia Vilahur

European Chemical Agency (ECHA)

Finland

Member

Maria Albin
Karolinska Institutet

Sweden

Member

Isabelle Baldi

Bordeaux University

France

Member

Dario Consonni
Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico

Italy

Member

Quentin Crowley

Trinity College Dublin

Ireland

Member

Béatrice Fervers

Comprehensive Cancer Center Léon Bérard

France

Member

Rüdiger Greinert

Skin Cancer Center Buxtehude

Germany

Member

Gerard Hoek

Utrecht University

Netherlands

Member

Sylvia Jochems

Utrecht University

Netherlands

Member

Martin Röösli

Swiss Tropical and Public Health Institute

Switzerland

Member

Martie van Tongeren

University of Manchester

United Kingdom

Working Group 3 Infections

Role

Name

Institute
Country
Chair
Silvia Franceschi

Centro di Riferimento Oncologico (CRO), IRCCS

Italy

Member

Nienke Alberts

Gemeente Amsterdam Public Health Service (GGD)

Netherlands

Member

Paul Bloem

World Health Organization (WHO)

Switzerland

Member

Sophie Grabar

Sorbonne Université & INSERM URMS 1136

France

Member

Mārcis Leja

University of Latvia

Latvia

Member

Peter Malfertheiner

LMU Klinikum

Germany

Member

Mojca Matičič

University Medical Centre Ljubljana & University of Ljubljana

Slovenia

Member

Francis Mégraud

INSERM U1312 BRIC

France

Member

Francisco Negro

University of Geneva

Switzerland

Member

Martyn Plummer

University of Warwick

United Kingdom

Member

Maarten Schim van der Loeff

University of Amsterdam & Gemeente Amsterdam Public Health Service (GGD)

Netherlands

Member

Silvia de Sanjosé

Barcelona Institute for Global Health, ISGlobal

Spain

Working Group 4 Medical Interventions

Role

Name

Institute
Country
Chair
Iris Lansdorp-Vogelaar

Erasmus University Medical Center (Erasmus MC)

Netherlands

Deputy Chair

Urška Ivanuš

Institute of Oncology Ljubljana

Slovenia

Member

Marc Arbyn

Sciensano

Belgium

Member

Anssi Auvinen

Tampere University

Finland

Member

David Baldwin

Nottingham City Hospital

United Kingdom

Member

Xavier Castells

Universitat Autònoma de Barcelona

Spain

Member

Andrea De Censi

National Hospital E.O. Ospedali Galliera

Italy

Member

Solveig Hofvind

Cancer Registry of Norway

Norway

Member

Carlo Senore

CPO Piemonte

Italy
Member

Mangesh Thorat

Queen Mary University of London
United Kingdom
Member

Esther Toes-Zoutendijk

Erasmus University Medical Center (Erasmus MC)

Netherlands

Member

Carlijn van der Aalst

Erasmus University Medical Center (Erasmus MC)

Netherlands

Working Group 5 Communication & Health Literacy

Role

Name

Institute
Country
Chair

Theresa Marteau

University of Cambridge

United Kingdom
Member

Alina Bârgăoanu

National University of Political Studies and Public Administration

Romania

Member

Kathelijne Bessems

Maastricht University

Netherlands

Member

Janne Bigaard

Danish Cancer Society

Denmark

Member

Kate Brain

University of Cardiff

United Kingdom
Member

Cristiana Fonseca

Portuguese League Against Cancer

Portugal

Member

Ulrike Helbig

German Cancer Aid

Germany

Member

Paweł Koczkodaj

Maria Skłodowska-Curie National Research Institute of Oncology

Poland

Member

Eleni Mantzari

University of Cambridge

United Kingdom
Member

Dafina Petrova

CIBER of Epidemiology and Public Health & Andalusian School of Public Health

Spain

Member

Violaine Roggeri

European Agency for Safety and Health at Work (EU-OSHA)

Spain

Member

Milka Sokolović

European Public Health Alliance (EPHA)

Belgium